Publications

Klempt P, Brzon O, Kasny M, Kvapilova K, Hubacek P, Briksi A, et al. Distribution of SARS-CoV-2 Lineages in the Czech Republic, Analysis of Data from the First Year of the Pandemic. Microorganisms. 2021;9(8).

Ligasova A, Koberna K. Strengths and Weaknesses of Cell Synchronization Protocols Based on Inhibition of DNA Synthesis. International Journal of Molecular Sciences. 2021;22(19).

Ligasova A, Koberna K. DNA Dyes-Highly Sensitive Reporters of Cell Quantification: Comparison with Other Cell Quantification Methods. Molecules. 2021;26(18).

Ligasova A, Rosenberg I, Bockova M, Homola J, Koberna K. Anchored linear oligonucleotides: the effective tool for the real-time measurement of uracil DNA glycosylase activity. Open Biology. 2021;11(10).

Raffaele M, Kovacovicova K, Biagini T, Lo Re O, Frohlich J, Giallongo S, et al. Nociceptin/orphanin FQ opioid receptor (NOP) selective ligand MCOPPB links anxiolytic and senolytic effects. Geroscience.

Reissig F, Bauer D, Zarschler K, Novy Z, Bendova K, Ludik MC, et al. Towards Targeted Alpha Therapy with Actinium-225: Chelators for Mild Condition Radiolabeling and Targeting PSMA-A Proof of Concept Study. Cancers. 2021;13(8).

Rimpelova S, Zimmermann T, Drasar PB, Dolensky B, Bejcek J, Kmonickova E, et al. Steroid Glycosides Hyrcanoside and Deglucohyrcanoside: On Isolation, Structural Identification, and Anticancer Activity. Foods. 2021;10(1).

Annadurai N, Malina L, Salmona M, Diomede L, Bastone A, Cagnotto A, et al. Antitumour drugs targeting tau R3 VQIVYK and Cys322 prevent seeding of endogenous tau aggregates by exogenous seeds. Febs Journal.

Jaworek H, Koudelakova V, Oborna I, Zborilova B, Brezinova J, Ruzickova D, et al. Impact of human papillomavirus infection on semen parameters and reproductive outcomes. Reproductive Biology and Endocrinology. 2021;19(1).

Kotulova J, Hajduch M, Dzubak P. Current Adenosinergic Therapies: What Do Cancer Cells Stand to Gain and Lose? International Journal of Molecular Sciences. 2021;22(22).

Porubsky M, Gurska S, Stankova J, Hajduch M, Dzubak P, Hlavac J. AminoBODIPY Conjugates for Targeted Drug Delivery Systems and Real-Time Monitoring of Drug Release. Molecular Pharmaceutics. 2021;18(6):2385-96.

Porubsky M, Vychodilova K, Milicevic D, Budesinsky M, Stankova J, Dzubak P, et al. Cytotoxicity of Amino-BODIPY Modulated via Conjugation with 2-Phenyl-3-Hydroxy-4(1H)-Quinolinones. Chemistryopen. 2021;10(11):1104-10.

Pokorny J, Olejnikova D, Frydrych I, Liskova B, Gurska S, Benicka S, et al. Substituted dienes prepared from betulinic acid - Synthesis, cytotoxicity, mechanism of action, and pharmacological parameters. European Journal of Medicinal Chemistry. 2021;224.

Malandra A, Rahman WU, Klimova N, Streparola G, Holubova J, Osickova A, et al. Bordetella Adenylate Cyclase Toxin Elicits Airway Mucin Secretion through Activation of the cAMP Response Element Binding Protein. International Journal of Molecular Sciences. 2021;22(16).

Holubova J, Juhasz A, Masin J, Stanek O, Jurnecka D, Osickova A, et al. Selective Enhancement of the Cell-Permeabilizing Activity of Adenylate Cyclase Toxin Does Not Increase Virulence of Bordetella pertussis. International Journal of Molecular Sciences. 2021;22(21).

Espinosa-Vinals CA, Masin J, Holubova J, Stanek O, Jurnecka D, Osicka R, et al. Almost half of the RTX domain is dispensable for complement receptor 3 binding and cell-invasive activity of the Bordetella adenylate cyclase toxin. Journal of Biological Chemistry. 2021;297(1).

Lepesheva A, Osickova A, Holubova J, Jurnecka D, Knoblochova S, Espinosa-Vinals C, et al. Different roles of conserved tyrosine residues of the acylated domains in folding and activity of RTX toxins. Scientific Reports. 2021;11(1).

Heine V, Hovorkova M, Vlachova M, Filipova M, Bumba L, Janouskova O, et al. Immunoprotective neo-glycoproteins: Chemoenzymatic synthesis of multivalent glycomimetics for inhibition of cancer-related galectin-3. European Journal of Medicinal Chemistry. 2021;220.

Malcova I, Bumba L, Uljanic F, Kuzmenko D, Nedomova J, Kamanova J. Lipid binding by the N-terminal motif mediates plasma membrane localization of Bordetella effector protein BteA. Journal of Biological Chemistry. 2021;296.

Knuutila A, Barkoff AM, Mertsola J, Osicka R, Sebo P, He QS. Simultaneous Determination of Antibodies to Pertussis Toxin and Adenylate Cyclase Toxin Improves Serological Diagnosis of Pertussis. Diagnostics. 2021;11(2).

Gong BS, Li D, Kusko R, Novoradovskaya N, Zhang YF, Wang SZ, et al. Cross-oncopanel study reveals high sensitivity and accuracy with overall analytical performance depending on genomic regions. Genome Biology. 2021;22(1).

Ledererova A, Dostalova L, Kozlova V, Peschelova H, Ladungova A, Culen M, et al. Hypermethylation of CD19 promoter enables antigen-negative escape to CART-19 in vivo and in vitro. Journal for Immunotherapy of Cancer. 2021;9(8).

Rossner P, Cervena T, Vojtisek-Lom M, Neca J, Ciganek M, Vrbova K, et al. Markers of lipid oxidation and inflammation in bronchial cells exposed to complete gasoline emissions and their organic extracts. Chemosphere. 2021;281.

Sima M, Rossnerova A, Simova Z, Rossner P. The Impact of Air Pollution Exposure on the MicroRNA Machinery and Lung Cancer Development. Journal of Personalized Medicine. 2021;11(1).

Cervena T, Rossnerova A, Zavodna T, Sikorova J, Vrbova K, Milcova A, et al. Testing Strategies of the In Vitro Micronucleus Assay for the Genotoxicity Assessment of Nanomaterials in BEAS-2B Cells. Nanomaterials. 2021;11(8).

Libalova H, Zavodha T, Vrbova K, Sikorova J, Vojtisek-Lom M, Beranek V, et al. Transcription profiles in BEAS-2B cells exposed to organic extracts from particulate emissions produced by a port-fuel injection vehicle, fueled with conventional fossil gasoline and gasoline-ethanol blend. Mutation Research-Genetic Toxicology and Environmental Mutagenesis. 2021;872.

Rossner P, Cervena T, Vojtisek-Lom M. In vitro exposure to complete engine emissions - a mini-review. Toxicology. 2021;462.

Urbanova K, Seifert D, Vinsova H, Vlk M, Lebeda O. Simple new method for labelling of PSMA-11 with Ga-68 in NaHCO3. Applied Radiation and Isotopes. 2021;172.

Krepela E, Vanickova Z, Hrabal P, Zubal M, Chmielova B, Balaziova E, et al. Regulation of Fibroblast Activation Protein by Transforming Growth Factor Beta-1 in Glioblastoma Microenvironment. International Journal of Molecular Sciences. 2021;22(3).

Balaziova E, Vymola P, Hrabal P, Mateu R, Zubal M, Tomas R, et al. Fibroblast Activation Protein Expressing Mesenchymal Cells Promote Glioblastoma Angiogenesis. Cancers. 2021;13(13).

Kolouchova K, Groborz O, Cernochova Z, Skarkova A, Brabek J, Rosel D, et al. Thermo- and ROS-Responsive Self-Assembled Polymer Nanoparticle Tracers for F-19 MRI Theranostics. Biomacromolecules. 2021;22(6):2325-37.

Albuquerque LJC, Sincari V, Jager A, Kucka J, Humajova J, Pankrac J, et al. pH-responsive polymersome-mediated delivery of doxorubicin into tumor sites enhances the therapeutic efficacy and reduces cardiotoxic effects. Journal of Controlled Release. 2021;332:529-38.

Pomeislová, A.; Otmar, M.; Rubešová, P.; Benýšek, J.; Matoušová, M.; Mertlíková-Kaiserová, H.; Pohl, R.; Poštová Slavětínská, L.; Pomeisl, K.; Krečmerová, M. 1,2,4-Thiadiazole Acyclic Nucleoside Phosphonates as Inhibitors of Cysteine Dependent Enzymes Cathepsin K and GSK-3β. Bioorg. Med. Chem. 2021, 32, Article No. 115998.

Onwubiko, N. O.; Diaz, S.; Krečmerová, M.; Nasheuer, H. P. Alkoxyalkyl Esters of Nucleotide Analogs Inhibit Polyomavirus DNA Replication and Large T Antigen Activities. Antimicrob. Agents Chemother. 2021, 65, Article No. e01641-20.

Reiberger, R.; Radilová, K.; Král, M.; Zima, V.; Majer, P.; Brynda, J.; Dračínský, M.; Konvalinka , J.; Kožíšek, M.; Machara, A. Synthesis and In Vitro Evaluation of C-7 and C-8 Luteolin Derivatives as Influenza Endonuclease Inhibitors. Int. J. Mol. Sci. 2021, 22, Article No. 7735.

Hejdánek, J.; Radilová, K.; Pachl, P.; Hodek, J.; Machara, A.; Weber, J.; Řezáčová, P.; Konvalinka, J.; Kožíšek, M. Structural characterization of the interaction between the C-terminal domain of the influenza polymerase PA subunit and an optimized small peptide inhibitor . Antiviral Res. 2021, 185, Article No. 104971.

Miláček, M.; Bittová, L.; Tůmová, Š.; Luksan, O.; Hanus, R.; Kyjaková, P.; Machara, A.; Marek, A. Binding of de novo synthesized radiolabeled juvenile hormone (JH III) by JH receptors from the Cuban subterranean termite Prorhinotermes simplex and the German cockroach Blattella germanica. Insect Biochem. Mol. Biol. 2021, 139, Article No. 103671.

Kejík, Z.; Kaplánek, R.; Dytrych, P.; Masařík, M.; Veselá, K.; Abramenko, N.; Hoskovec, D.; Vašáková, M.; Králová, J.; Martásek, P.; Jakubek, M., Circulating Tumour Cells (CTCs) in NSCLC: From Prognosis to Therapy Design. Pharmaceutics 2021, 13 (11). DOI: 10.3390/pharmaceutics13111879

Kejik, Z.; Kaplanek, R.; Masarik, M.; Babula, P.; Matkowski, A.; Filipensky, P.; Vesela, K.; Gburek, J.; Sykora, D.; Martasek, P.; Jakubek, M., Iron Complexes of Flavonoids-Antioxidant Capacity and Beyond. Int. J. Mol. Sci. 2021, 22 (2), 20. DOI: 10.3390/ijms22020646

Abramenko, N.; Kejik, Z.; Kaplanek, R.; Tatar, A.; Brogyanyi, T.; Pajkova, M.; Sykora, D.; Vesela, K.; Antonyova, V.; Dytrych, P.; Ikeda-Saito, M.; Martasek, P.; Jakubek, M., Spectroscopic study of in situ-formed metallocomplexes of proton pump inhibitors in water. Chem. Biol. Drug Des. 2021, 97 (2), 305-314. DOI: 10.1111/cbdd.13782

Fialova Leischner, J.; Raudenska, M.; Jakubek, M.; Kejik, Z.; Martasek, P.; Babula, P.; Matkowski, A.; Filipensky, P.; Masarik, M., Novel Mitochondria-targeted Drugs for Cancer Therapy. Mini-Reviews in Medicinal Chemistry 2021, 21 (7), 816-832. DOI: 10.2174/1389557520666201118153242

Lejdarova H, Pacasova R, Tesarova L, Koutna I, Polokova N, Michlickova S, et al. Cryopreserved buffy-coat-derived platelets reconstituted in platelet additive solution: A safe and available product with sufficient haemostatic effectiveness. Transfusion and Apheresis Science. 2021;60(3).

Simara P, Tesarova L, Tapuchova I, Celerova J, Koutna I. T-Cell Activation: Post-Infection Diagnostic Tool for COVID-19. Folia Biologica. 2021;67(1):16-27.