Publications

DVOŘÁKOVÁ, P., P. BUŠEK, T. KNEDLÍK, J. SCHIMER, T. ETRYCH, L. KOSTKA, L. STOLLINOVÁ ŠROMOVÁ, V. ŠUBR, P. ŠÁCHA, A. ŠEDO, J. KONVALINKA. Inhibitor-Decorated Polymer Conjugates Targeting Fibroblast Activation Protein. Journal of Medicinal Chemistry. 2017, 60 (20), 8385-8393. ISSN: 1520-4804. IF: 6.259. PMID: 28953383

MATRASOVA, I., P. BUSEK, E. BALAZIOVA, A. SEDO. Heterogeneity of molecular forms of dipeptidyl peptidase-IV and fibroblast activation protein in human glioblastomas. Biomedical papers of the Medical Faculty of Palacký University, Olomouc, Czech Republic. 2017, 161 (3), 252-260. ISSN: 1213-8118. IF 0.894. PMID: 28452380

PILAŘ, J., M. ŠLOUF, D. MICHÁLKOVÁ, I. ŠLOUFOVÁ, T. VACKOVÁ, J. DYBAL. Pro-oxidant activity of α-tocopherol during photooxidative degradation of polyolefins. ESRI and IR microspectroscopy studies. Polymer Degradation and Stability. 2017, 138, 55-71, ISSN: 0141-3910. IF: 3.193

HÖCHERL, A., E. JÄGER, O. JANOUŠKOVÁ, P. ŠTĚPÁNEK, M. HRUBÝ. Reactive oxygen species-cleavable self-immolative diethylstilbestrol polyester nanoparticles give rise to cancer hormone therapy with minimized side effects. Journal of Controlled Release. 2017, 259, e7-e8, ISSN: 0168-3659. IF: 7.877. 

MACHOVÁ-URDZÍKOVÁ, L., J. RŮŽIČKA, K. KÁROVÁ, A. KLOUDOVÁ, B. SVOBODOVÁ, A. ANUBHAV, J. DUBIŠOVÁ, M. SCHMIDT, Š. KUBINOVÁ, M. JHANWAR UNIYAL, P. JENDELOVÁ. A green tea polyphenol epigallocatechin-3-gallate enhances neuroregeneration after spinal cord injury by altering levels of inflammatory cytokines. Neuropharmacology. 2018, 126, 213-223. ISSN: 0028-3908. IF: 4.249. PMID: 28899730

SYKOVÁ, E., P. RYCHMACH, I. DRAHORÁDOVÁ, Š KONRÁDOVÁ, K. RŮŽIČKOVÁ, I. VOŘÍŠEK, S. FOROSTYAK, A. HOMOLA, M. BOJAR. Transplantation of Mesenchymal Stromal Cells in Patients With Amyotrophic Lateral Sclerosis: Results of Phase I/IIa Clinical Trial. Cell Transplantation. 2017 26 (4), 647-658. ISSN: 1555-3892. IF: 2.885. PMID: 27938483

RŮŽIČKA, J., L. MACHOVÁ URDZIKOVÁ, J. GILLICK, T. AMEMORI, N. ROMAYUK, K. KÁROVÁ, K. ZÁVIŠKOVÁ, J. DUBIŠOVÁ, Š. KUBINOVÁ, R. MURALI, E. SYKOVÁ, M. JHANWAR-UNIYAL, P. JENDELOVÁ. A Comparative Study of Three Different Types of Stem Cells for Treatment of Rat Spinal Cord Injury. Cell Transplantation. 2017, 26 (4), 585-603. ISSN: 1555-3892. IF: 2.885. PMID: 27938489    

LUKOVIC, D., A. DIEZ LLORET, P. STOJKOVIC, D. RODRÍGUEZ-MARTÍNEZ, M. P. P.  ARAGO, F. J. RODRIGUEZ-JIMÉNEZ, P. GONZÁLEZ-RODRÍGUEZ, J. LÓPEZ-BARNEO, E. SYKOVÁ, P. JENDELOVÁ, J. KOSTIC, V. MORENO-MANZANO, M. STOJKOVIC, S. S. BHATTACHARYA, S. ERCEG. Highly Efficient Neural Conversion of Human Pluripotent Stem Cells in Adherent and Animal-Free Conditions. Stem Cells Translational Medicine. 2017, 6 (4), 1217-1226. ISSN: 2157-6564. IF: 4.929. PMID: 28213969.

KUBINOVA, S., K. ZAVISKOVA, L. UHERKOVA, V. ZABLOTSKII, O. CHURPITA, O. LUNOV, A. DEJNEKA. Non-thermal air plasma promotes the healing of acute skin wounds in rats. Scientific Reports. 2017, 7, 45183. ISSN: 2045-2322. IF: 4.122. PMID: 28338059

PETRENKO, Y., E. SYKOVÁ, Š. KUBINOVÁ. The therapeutic potential of three-dimensional multipotent mesenchymal stromal cell spheroids. Stem Cell Research & Therapy. 2017, 8 (1), 94. ISSN: 1757-6512. IF: 3.77. PMID: 28446248

CEJKA, C., J. KOSSL, B. HERMANKOVA, V. HOLAN, S. KUBINOVA, ZHANG, JH., CEJKOVA, J. Therapeutic effect of molecular hydrogen in corneal UVB-induced oxidative stress and corneal photodamage. Scientific Reports. 2017, 7, 18017. ISSN: 2045-2322. IF: 4.122. PMID: 29269749.

ONDRÁČEK, J., P. FADRUS, J. ŠÁNA, A. BEŠŠE, T. LOJA, M. VEČEŘA, L. RADOVÁ, M. SMRČKA, P. ŠLAMPA, O. SLABÝ. Global MicroRNA Expression Profiling Identifies Unique MicroRNA Pattern of Radioresistant Glioblastoma Cells. Anticancer Research. 2017, 37 (3), 1099-1104. ISSN: 0250-7005. IF: 1.865. PMID: 28314270

VÁVROVÁ, E., B. KANTOROVÁ, B. VONKOVÁ, J. KABÁTHOVÁ, H. SKUHROVA-FRANCOVA, E. DIVÍŠKOVÁ, O. LETOCHA, J. KOTAŠKOVÁ, Y. BRYCHTOVÁ, M. DOUBEK, J. MAYER, Š. POSPÍŠILOVÁ. Fragment analysis represents a suitable approach for the detection of hotspot c.7541_7542delCT NOTCH1 mutation in chronic lymphocytic leukemia. Leukemia Research. 2017, 60, 145-150. ISSN: 0145-2126. IF: 2.319. PMID: 28837890

WALD, T., F. SPOUTIL, A. OSICKOVA, M. PROCHAZKOVA, O. BENADA, P. KASPAREK, L. BUMBA, O. D. KLEINE, R. SEDLACEK, P. SEBO, J. PROCHAZKA, R. OSICKA. Intrinsically disordered proteins drive enamel formation via an evolutionarily conserved self-assembly motif. Proceedings of the National Academy of Sciences of the United States of America. 2017, 114 (9), E1641-E1650. ISSN: 1091-6490. IF=9.504. PMID: 28196895

CERNY, O., K. E. ANDERSON, L. R. STEPHENS, P. T. HAWKINS, P. SEBO. cAMP Signaling of Adenylate Cyclase Toxin Blocks the Oxidative Burst of Neutrophils through Epac-Mediated Inhibition of Phospholipase C Activity. Journal of Immunology. 2017, 198 (3), 1285-1296. ISSN: 1550-6606. IF: 4.539. PMID: 28039302

SVIRIDOVA, E., P. REZACOVA, A. BONDAR, V. VEVERKA, P. NOVAK, G. SCHENK, D. I. SVERGUN, I. KUTA SMATANOVA, L. BUMBA. Structural basis of the interaction between the putative adhesion-involved and iron-regulated FrpD and FrpC proteins of Neisseria meningitidis. 2017, 7, 40408. ISSN: 2045-2322. IF: 4.529. PMID: 28084396

SKOPOVA, K., B. TOMALOVA, I. KANCHEV, P. ROSSMANN, M. SVEDOVA, I. ADKINS, I. BIBOVA, J. TOMALA, J. MASIN, N. GUISO, R. OSICKA, R. SEDLACEK, M. KOVAR, P. SEBO. Cyclic AMP-Elevating Capacity of Adenylate Cyclase Toxin-Hemolysin Is Sufficient for Lung Infection but Not for Full Virulence of Bordetella pertussis. Infection and Immunity. 2017, 85 (6), pii: e00937-16. ISSN: 1098-5522. IF: 3.256. PMID: 28396322
 
MASIN, J., J. RODEROVA, A. OSICKOVA, P. NOVAK, L. BUMBA, R. FISER, P. SEBO, R. OSICKA. The conserved tyrosine residue 940 plays a key structural role in membrane interaction of Bordetella adenylate cyclase toxin. Scientific Reports. 2017, 7, 9330. ISSN: 2045-2322. IF: 4.529. PMID: 28839199

NOVAK, J., O. CERNY, A. OSICKOVA, I. LINHARTOVA, J. MASIN, L. BUMBA, P. SEBO, R. OSICKA. Structure-Function Relationships Underlying the Capacity of Bordetella Adenylate Cyclase Toxin to Disarm Host Phagocytes. Toxins. 2017, 9 (10), pii: E300. ISSN: 2072-6651. IF= 3.273. PMID: 28946636

USSI, A., M. DE KORT, N. COUSSENS, T. AITTOKALLIO, M. HAJDÚCH. In Search of System-Wide Productivity Gains - The Role of Global Collaborations in Preclinical Translation. Clinical and Translational Science. 2017, 10 (6), 423-425. ISSN: 1752-8054. IF: 0.860. PMID: 28929592

VOLLER, J., T. BERES, M. ZATLOUKAL, P. KAMINSKI, P. NIEMANN, K. DOLEZAL, P. DŽUBÁK, M. HAJDÚCH, M. STRNAD. The natural cytokinin 2OH3MeOBAR induces cell death by a mechanism that is different from that of the "classical" cytokinin ribosides. Phytochemistry. 2017, 136, 156-164. ISSN: 1873-3700. IF: 2.779. PMID: 28153445

LIGASOVÁ, A., P. KONEČNÝ, I. FRYDRYCH, K. KOBERNA. Looking for ugly ducklings: The role of the stability of BrdU-antibody complex and the improved method of the detection of DNA replication. PLOS One. 2017, 12 (3), e0174893. ISSN: 1932-6203. IF: 3.057. PMID: 28358913

LIGASOVÁ, A., P. KONEČNÝ, I. FRYDRYCH, K. KOBERNA. Cell cycle profiling by image and flow cytometry: The optimised protocol for the detection of replicational activity using 5-Bromo-2'-deoxyuridine, low concentration of hydrochloric acid and exonuclease III. PLOS One. 2017, 12 (4), e0175880. ISSN: 1932-6203. IF: 3.057. PMID: 28426799

OŽDIAN, T., D. HOLUB, Z. MACEČKOVÁ, L. VARANASI, G. RYLOVÁ, J. ŘEHULKA, J. VÁCLAVKOVÁ, H. SLAVÍK, P. MOUDRÝ, P. ZNOJEK, J. STANKOVÁ, J. DE SANCTIS, M. HAJDÚCH, P. DŽUBÁK. Proteomic profiling reveals DNA damage, nucleolar and ribosomal stress are the main responses to oxaliplatin treatment in cancer cells. Journal of Proteomics. 2017, 162, 73-85. ISSN: 1874-3919. IF: 3.867. PMID: 28478306

PANT, K., O. SEDLÁČEK, R. A. NADAR, M. HRUBÝ, H. STEPHAN. Radiolabelled polymeric materials for imaging and treatment of cancer: Quo vadis? Advanced Healthcare Materials. 2017, 6 (6), 1601115_1-1601115_31. ISSN: 2192-2659. IF: 5.609. PMID: 28218487  

MEDEL, S., Z. SYROVÁ, L. KOVÁČIK, J. HRDÝ, M. HORNACEK, E. JAGER, M. HRUBÝ, R. LUND, D CMARKO, P. ŠTĚPÁNEK, I. RAŠKA, B. NYSTRÖM. Curcumin-bortezomib loaded polymeric nanoparticles for synergistic cancer therapy. European Polymer Journal. 2017, 93, 116-131. ISSN: 0014-3057. IF: 3.741. 

BREZANIOVÁ, I., J. TROUSIL , Z. ČERNOCHOVÁ, V. KRÁL, M. HRUBÝ, P. ŠTĚPÁNEK, M. ŠLOUF. Self-assembled chitosan-alginate polyplex nanoparticles containing temoporfin. Colloid and Polymer Science. 2017, 295 (8), 1259-1270. ISSN: 1435-1536. IF: 1.967.

ŠKROTT, Z., M. MISTRÍK, K. ANDERSEN, S. FRIIS, D. MAJERA, J. GURSKÝ, T. OŽDIAN, J. BARTKOVA, Z. TURI, P. MOUDRÝ, M. KRAUS, M. MEDVEDÍKOVÁ, J. VÁCLAVKOVÁ, P. DŽUBÁK, I. VROBEL, P. POUCKOVA, J. SEDLACEK, A. MIKLOVICOVA, A. KUTT, J. MATTOVA, C. DRIESSEN, Q. DOU, J. OLSEN, M. HAJDÚCH, B. CVEK, R. DESHAIES, J. BÁRTEK. Alcohol-abuse drug disulfiram targets cancer via p97 segregase adaptor NPL4. Nature. 2017, 552 (7684), 194-199. ISSN: 0028-0836. IF: 40.137. PMID: 29211715

LUPTAKOVA, D., T. PLUHACEK, M. PETŘÍK, J. NOVAK, A. PALYZOVA, L. SOKOLOVA, A. SKRIBA, B. SEDIVA, K. LEMR, V. HAVLICEK. Non-invasive and invasive diagnoses of aspergillosis in a rat model by mass spectrometry. Scientific Reports. 2017, 7 (1), 16523. ISSN: 2045-2322. IF: 4.529. PMID: 29184111

TOMANOVÁ, M., L. JEDINÁK, J. KOSAR, P. HRADIL, P. CANKAR. Synthesis of 4-substituted pyrazole-3,5-diamines via Suzuki-Miyaura coupling and iron-catalyzed reduction. Organic & Biomolecular Chemistry. 2017, 15 (48), 10200-10211. ISSN: 1477-0520. IF: 3.564. PMID: 29177274

KRAJČOVIČOVÁ, S., T. GUCKÝ, D. HENDRYCHOVA, V. KRYŠTOF, M. SOURAL. A Stepwise Approach for the Synthesis of Folic Acid Conjugates with Protein Kinase Inhibitors. Journal of Organic Chemistry. 2017, 82 (24), 13530-13541. ISSN: 1520-6904. IF: 4.849. PMID: 29171753

VÁCLAVÍK, J., K. COENE, I. VROBEL, L. NAJDEKR, D. FRIEDECKÝ, R. KARLÍKOVÁ, L. MÁDROVÁ, A. PETSALO, U. ENGELKE, A. VAN WEGBERG, L. KLUIJTMANS, T. ADAM, R. WEVERS. Structural elucidation of novel biomarkers of known metabolic disorders based on multistage fragmentation mass spectra. Journal of Inherited Metabolic Disease. 2017, 41 (3), 407-414. ISSN: 1573-2665. IF: 3.970. PMID: 29139026

KRASULOVÁ, K., O. HOLAS, P. ANZENBACHER. Influence of Amlodipine Enantiomers on Human Microsomal Cytochromes P450: Stereoselective Time-Dependent Inhibition of CYP3A Enzyme Activity. Molecules. 2017, 22 (11), pii: E1879. ISSN: 1420-3049. IF: 2.861. PMID: 29099769

LEMSTROVA, R., V. BRYNYCHOVA, D. HUGHES, V. HLAVAC, P. DVORAK, J. DOHERTY, H. MURRAY, M. CROCKARD, M. OLIVERIUS, J. HLAVSA, E. HONSOVA, J. MAZANEC, Z. KALA, M. LOVEČEK, R. HAVLÍK, J. EHRMANN, O. STROUHAL, P. SOUCEK, B. MELICHAR, B. MOHELNÍKOVÁ DUCHOŇOVÁ. Dysregulation of KRAS signaling in pancreatic cancer is not associated with KRAS mutations and outcome. Oncology Letters. 2017, 14 (5), 5980-5988. ISSN: 1792-1074. IF: 1.390. PMID: 29113235

MODER, M., G. VELIMEZI, M. OWUSU, A. MAZOUZI, M. WIEDNER, J. FERREIRA DA SILVA, L. ROBINSON-GARCIA, F. SCHISCHLIK, R. SLAVKOVSKÝ, R. KRALOVICS, B. SCHUSTER, C. BOCK, T. IDEKER, S. JACKSON, J. MENCHE, J. LOIZOU. Parallel genome-wide screens identify synthetic viable interactions between the BLM helicase complex and Fanconi anemia. Nature Communications. 2017, 8 (1), 1238. ISSN: 2041-1723. IF: 12.124. PMID: 29089570

NGUYEN, L., Z. MYSLIVECKOVA, B. SZOTAKOVA, A. ŠPIČÁKOVÁ, K. LNENICKOVA, M. AMBROZ, V. KUBICEK, K. KRASULOVÁ, P. ANZENBACHER, L. SKALOVA. The inhibitory effects of β-caryophyllene, β-caryophyllene oxide and α-humulene on the activities of the main drug-metabolizing enzymes in rat and human liver in vitro. Chemico-biological Interactions. 2017, 278, 123-128. ISSN: 0009-2797. IF: 3.143. PMID: 29074051

KRÁLOVÁ, P., M. MALOŇ, M. SOURAL. Stereoselective Synthesis of Benzo[e][1,4]oxazino[4,3-a][1,4]diazepine-6,12-diones with Two Diversity Positions. ACS Combinatorial Science. 2017, 19 (12), 770-774. ISSN: 2156-8952. IF: 3.168. PMID: 29048877

PACULOVA, H., J. KRAMARA, S. SIMECKOVA, R. FEDR, K. SOUCEK, O. HYLSE, K. PARUCH, M. SVOBODA, M. MISTRÍK, J. KOHOUTEK. BRCA1 or CDK12 loss sensitizes cells to CHK1 inhibitors. Tumor Biology. 2017, 39 (10), 1010428317727479. ISSN: 1010-4283. IF: 3.650. PMID: 29025359

EIGNEROVA, B., M. TICHÝ, K. KRASULOVÁ, L. RAROVA, R. CHRISTOVÁ, M. URBAN, B. BEDNARCZYK-CWYNAR, M. HAJDÚCH, J. ŠAREK. Q1_Synthesis and antiproliferative properties of new hydrophilic esters of triterpenic acids.European Journal of Medicinal Chemistry. 2017, 140, 403-420. ISSN: 0223-5234. IF: 4.519. PMID: 28987603

PLEVOVA, P., M. PAPRSKÁŘOVÁ, P. TVRDA, P. TURSKA, R. SLAVKOVSKÝ, E. MRAZKOVA. STRC Deletion is a Frequent Cause of Slight to Moderate Congenital Hearing Impairment in the Czech Republic. Otology & Neurotology. 2017, 38 (10), e393-e400. ISSN: 1531-7129. IF: 2.024. PMID: 28984810

KARLÍKOVÁ, R., K. MIČOVÁ, L. NAJDEKR, A. GARDLO, T. ADAM, P. MAJEROVÁ, D. FRIEDECKÝ, A. KOVAC. Metabolic status of CSF distinguishes rats with tauopathy from controls. Alzheimer's Research & Therapy. 2017, 9 (1), 78. ISSN: 1758-9193. IF: 6.154. PMID: 28934963

VRABLIKOVA, A., L. CZERNEKOVA, R. CAHLIKOVA, Z. NOVÝ, M. PETŘÍK, S. IMRAN, Z. NOVÁK, M. KŘUPKA, V. CEROVSKY, J. TURANEK, M. RAŠKA. Lasioglossins LLIII affects the morphogenesis of Candida albicans and reduces the duration of experimental vaginal candidiasis in mice. Microbiology and Immunology. 2017, 61 (11), 474-481. ISSN: 0385-5600. IF: 1.706. PMID: 28892177

VRZALIKOVA, K., M. IBRAHIM, M. VOCKERODT, T. PERRY, S. MARGIELEWSKA, L. LUPINO, E. NAGY, E. SOILLEUX, D. LIEBELT, R. HOLLOWS, A. LAST, G. REYNOLDS, M. ABDULLAH, H. CURLEY, M. CARE, D. KRAPPMANN, R. TOOZE, J. ALLEGOOD, S. SPIEGEL, W. WEI, C. WOODMAN, P. MURRAY. S1PR1 drives a feedforward signalling loop to regulate BATF3 and the transcriptional programme of Hodgkin lymphoma cells. Leukemia. 2017, 32 (1), 214-223. ISSN: 0887-6924. IF: 11.702. PMID: 28878352

EFFENBERG, R., P. TURANEK KNOTIGOVA, D. ZYKA, H. CELECHOVSKA, J. MASEK, E. BARTHELDYOVA, F. HUBATKA, S. KOUDELKA, R. LUKAC, A. KOVALOVA, D. SAMAN, M. KŘUPKA, L. BARKOCZIOVA, P. KOSZTYU, M. ŠEBELA, L. DROZ, M. HUCKO, M. KANASKOVA, A. MILLER, M. RAŠKA, M. LEDVINA, J. TURANEK. Nonpyrogenic Molecular Adjuvants Based on norAbu-Muramyldipeptide and norAbu-Glucosaminyl Muramyldipeptide: Synthesis, Molecular Mechanisms of Action, and Biological Activities in Vitro and in Vivo. Journal of Medicinal Chemistry. 2017, 60 (18), 7745-7763. ISSN: 0022-2623. IF: 6.259. PMID: 28829599

KRÁLOVÁ, P., M. MALOŇ, T. VOLNÁ, V. RUČILOVÁ, M. SOURAL. Polymer-Supported Stereoselective Synthesis of Benzoxazino[4,3-b][1,2,5]thiadiazepinone 6,6-dioxides. ACS Combinatorial Science. 2017, 19 (10), 670-674. ISSN: 2156-8952. IF: 3.168. PMID: 28825802

POLISHCHUK, P., T. MADZHIDOV, T. GIMADIEV, A. BODROV, R. NUGMANOV, A. VARNEK. Structure-reactivity modeling using mixture-based representation of chemical reactions. Journal of Computer-aided Molecular Design. 2017, 31 (9), 829-839. ISSN: 1573-4951. IF: 3.028. PMID: 28752345

GARIC, D., J. DE SANCTIS, G. WOJEWODKA, D. HOULE, S. CUPRI, A. ABU-ARISH, J. HANRAHAN, M. HAJDÚCH, E. MATOUK, D. RADZIOCH. Fenretinide differentially modulates the levels of long- and very long-chain ceramides by downregulating Cers5 enzyme: evidence from bench to bedside. Journal of Molecular Medicine. 2017, 95 (10), 1053-1064. ISSN: 2869-5226. IF: 4.686. PMID: 28695226

JÁČOVÁ, J., A. GARDLO, D. FRIEDECKÝ, T. ADAM, J. DIMANDJA. Sample-independent approach to normalize two-dimensional data for orthogonality evaluation using whole separation space scaling. Journal of Chromatography. A. 2017, 1511, 1-8. ISSN: 0021-9673. IF: 3.981. PMID: 28693825

KLIMENKO, K., S. LYAHKOV, M. SHIBINSKAYA, A. KARPENKO, G. MARCOU, D. HORVATH, M. ZENKOVA, E. GONCHAROVA, R. AMIRKHANOV, A. KRYSKO, S. ANDRONATI, I. LEVANDOVSKIY, P. POLISHCHUK, V. KUZMIN, A. VARNEK. Virtual screening, synthesis and biological evaluation of DNA intercalating antiviral agents. Bioorganic & Medicinal Chemistry Letters. 2017, 27 (16), 3915-3919. ISSN: 1464-3405. IF: 2.454. PMID: 28666733

FUNK, P., K. MOTYKA, M. SOURAL, M. MALOŇ, H. KOSHINO, J. KUSZ, J. HLAVÁČ. Study of 2-aminoquinolin-4(1H)-one under Mannich and retro-Mannich reaction. PLOS One. 2017, 12 (5), e0175364. ISSN: 1932-6203. IF: 3.057. PMID: 28557987

NARDONE, G., J. OLIVER-DE LA CRUZ, J. VRBSKY, C. MARTINI, J. PRIBYL, P. SKLADAL, M. PESL, G. CALUORI, S. PAGLIARI, F. MARTINO, Z. MACEČKOVÁ, M. HAJDÚCH, A. SANZ-GARCIA, N. PUGNO, G. STOKIN, G. FORTE. YAP regulates cell mechanics by controlling focal adhesion assembly. Nature Communications. 2017, 8, 15321. ISSN: 2041-1723. IF: 11.329. PMID: 28504269

GACHECHILADZE, M., J. ŠKARDA, A. SOLTERMANN, M. JOERGER. RAD51 as a potential surrogate marker for DNA repair capacity in solid malignancies. International Journal of Cancer. 2017, 141 (7), 1286-1294. ISSN: 0020-7136. IF: 5.531. PMID: 28477336

WOLIN, A., E. LAHTELA, V. ANTTILA, M. PETŘEK, J. GRUNEWALD, C. VAN MOORSEL, A. EKLUND, J. GRUTTERS, V. KOLEK, F. MRÁZEK, A. KISHORE, L. PADYUKOV, A. PIETINALHO, M. RONNINGER, M. SEPPÄNEN, O. SELROOS, M. LOKKI. SNP Variants in Major Histocompatibility Complex Are Associated with Sarcoidosis Susceptibility—A Joint Analysis in Four European Populations. Frontiers in Physiology. 2017, 8, 422. ISSN: 1664-3224. IF: 5.695. PMID: 28469621

SUMMER, D., L. GROSSRUBATSCHER, M. PETŘÍK, T. MICHALČÍKOVÁ, Z. NOVÝ, C. RANGGER, M. KLINGER, E. VON GUGGENBERG, R. HAUBNER, P. KAEOPOOKUM, H. HAAS, C. DECRISTOFORO. Developing targeted hybrid imaging probes by chelator scaffolding. Bioconjugate Chemistry. 2017, 28 (6), 1722-1733. ISSN: 1043-1802. IF: 4.500. PMID: 28462989

VAN GOOL, A., F. BIETRIX, E. CALDENHOVEN, K. ZATLOUKAL, A. SCHERER, J. LITTON, G. MEIJER, N. BLOMBERG, A. SMITH, B. MONS, J. HERINGA, W. KOOT, M. SMIT, M. HAJDÚCH, T. RIJNDERS, A. USSI. Bridging the translational innovation gap through good biomarker practice. Nature Reviews. Drug Discovery. 2017, 16 (9), 587-588.ISSN: 1474-1776 . IF: 47.120. PMID: 28450744

PAJTAS, D., K. KONYA, A. KISS-SZIKSZAI, P. DŽUBÁK, Z. PETHO, Z. VARGA, G. PANYI, T. PATONAY. Optimization of the Synthesis of Flavone-Amino Acid and Flavone-Dipeptide Hybrids via Buchwald-Hartwig Reaction.Journal of Organic Chemistry. 2017, 82 (5), 4578-4587. ISSN: 0022-3263. IF: 4.785. PMID: 28441016

VAD DER STELT, I., F. HOEVENAARS, J. ŠIROKÁ, J. DE RONDE, D. FRIEDECKÝ, J. KEIJER, E. VAN SCHOTHORST. Metabolic Response of Visceral White Adipose Tissue of Obese Mice Exposed for 5 Days to Human Room Temperature Compared to Mouse Thermoneutrality. Frontiers in Physiology. 2017, 8, 179. ISSN: 1664-042X. IF: 4.031. PMID: 28386236

KAHOUNOVA, Z., D. KURFÜRSTOVÁ, J. BOUCHAL, G. KHARAISHVILI, J. NAVRATIL, J. REMSIK, S. SIMECKOVA, V. STUDENT, A. KOZUBIK, K. SOUCEK. The fibroblast surface markers FAP, anti-fibroblast, and FSP are expressed by cells of epithelial origin and may be altered during epithelial-to-mesenchymal transition. Cytometry A. 2017, 93 (9), 941-951. ISSN: 1552-4930. IF: 3.181. PMID: 28383825

ŘEHULKA, J., N. ANNADURAI, I. FRYDRYCH, P. ZNOJEK, P. DŽUBÁK, P. NORTHCOTE, J. MILLER, M. HAJDÚCH, V. DAS. Cellular effects of the microtubule-targeting agent peloruside A in hypoxia-conditioned colorectal carcinoma cells. Biochimica et Biophysica Acta. 2017, 1861 (7), 1833-1843. ISSN: 0304-4165. IF: 5.083. PMID: 28366502

ŠPIČÁKOVÁ, A., B. SZOTAKOVA, D. DIMUNOVA, Z. MYSLIVECKOVA, V. KUBICEK, M. AMBROZ, K. LNENICKOVA, K. KRASULOVÁ, P. ANZENBACHER, L. SKALOVA. Nerolidol and Farnesol Inhibit Some Cytochrome P450 Activities but Did Not Affect Other Xenobiotic-Metabolizing Enzymes in Rat and Human Hepatic Subcellular Fractions. Molecules. 2017, 22 (4), pii: E509. ISSN: 1420-3049. IF: 2.465. PMID: 28338641

JOUROVA, L., P. ANZENBACHER, B. LIŠKOVÁ, Z. MATUŠKOVÁ, P. HERMANOVA, T. HUDCOVIC, H. KOZAKOVA, L. HRNCIROVA, E. ANZENBACHEROVÁ. Colonization by non-pathogenic bacteria alters mRNA expression of cytochromes P450 in originally germ-free mice. Folia Microbiologica. 2017, 62 (6), 463-469. ISSN: 1874-9356. IF: 1.335. PMID: 28337589

VRÁNA, D., J. GATEK. Internal mammary lymph node management - further direction. OncoTargets and Therapy. 2017, 10, 1111-1114. ISSN: 1178-6930. IF: 2.272. PMID: 28260925

GACHECHILADZE, M., J. ŠKARDA, V. KOLEK, I. GRYGÁRKOVÁ, K. LANGOVA, J. BOUCHAL, Z. KOLÁŘ, F. BATY, R. STAHEL, W. WEDER, A. SOLTERMANN, M. JOERGER. Prognostic and predictive value of loss of nuclear RAD51 immunoreactivity in resected non-small cell lung cancer patients. Lung Cancer. 2017, 105, 31-38. ISSN: 0169-5002. IF: 3.767. PMID: 28236982

VESELÁ, E., K. CHROMÁ, Z. TURI, M. MISTRÍK. Common Chemical Inductors of Replication Stress: Focus on Cell-Based Studies. Biomolecules. 2017, 7 (1), pii: E19. ISSN: 2218-273X. IF: 2.127. PMID: 28230817

TICHÝ, M., S. SMOLEN, E. TLOUŠŤOVÁ, R. POHL, T. OŽDIAN, K. HEJTMÁNKOVÁ, B. LIŠKOVÁ, S. GURSKÁ, P. DŽUBÁK, M. HAJDÚCH, M. HOCEK. Synthesis and Cytostatic and Antiviral Profiling of Thieno-Fused 7-Deazapurine Ribonucleosides. Journal of Medicinal Chemistry. 2017, 60 (6), 2411-2424. ISSN: 0022-2623. IF: 5.589. PMID: 28221790

VRÁNA, D., M. MATZENAUER, R. AUJESKY, J. VRBA, C. NEORAL, B. MELICHAR, P. SOUCEK. Potential Predictive Role of MicroRNAs in the Neoadjuvant Treatment of Esophageal Cancer. Anticancer Research. 2017, 37 (2), 403-412. ISSN: 0250-7005. IF: 1.895. PMID: 28179285

ŠIDOVÁ, V., P. ZOUFALÝ, J. POKORNÝ, P. DŽUBÁK, M. HAJDÚCH, I. POPA, M. URBAN. Cytotoxic conjugates of betulinic acid and substituted triazoles prepared by Huisgen Cycloaddition from 30-azidoderivatives. PLOS One. 2017, 12 (2), e0171621. ISSN: 1932-6203. IF: 3.057. PMID: 28158265

GAYKALOVA, D., V. ŽIŽKOVÁ, T. GUO, I. TISCARENO, Y. WEI, R. VATAPALLI, P. HENNESSEY, J. AHN, L. DANILOVA, Z. KHAN, J. BISHOP, J. GUTKIND, W. KOCH, W. WESTRA, E. FERTIG, M. OCHS, J. CALIFANO. Integrative computational analysis of transcriptional and epigenetic alterations implicates DTX1 as a putative tumor suppressor gene in HNSCC. Oncotarget. 2017, 8 (9), 15349-15363. ISSN: 1949-2553. IF: 5.008. PMID: 28146432

BORKOVÁ, L., R. ADÁMEK, P. KALINA, P. DRAŠAR, P. DŽUBÁK, S. GURSKÁ, J. ŘEHULKA, M. HAJDÚCH, M. URBAN, J. ŠAREK. Synthesis and Cytotoxic Activity of Triterpenoid Thiazoles Derived from Allobetulin, Methyl Betulonate, Methyl Oleanonate, and Oleanonic Acid. ChemMedChem. 2017, 12 (5), 390-398. ISSN: 1860-7179. IF: 2.980. PMID: 28084676

JEDINÁK, L., R. ZATOPKOVA, H. ZEMANKOVA, A. SUSTKOVA: P. CANKAR. The Suzuki-Miyaura Cross-Coupling Reaction of Halogenated Aminopyrazoles: Method Development, Scope, and Mechanism of Dehalogenation Side Reaction. Journal of Organic Chemistry. 2017, 82 (1), 157-169. ISSN: 0022-3263. IF: 4.785. PMID: 27997179

RUČIL, T., Z. TRAVNICEK, P. CANKAR. Ring-Opening Reactions of the N-4-Nosyl Hough-Richardson Aziridine with Nitrogen Nucleophiles. Journal of Organic Chemistry. 2017, 82 (1), 723-730. ISSN: 0022-3263. IF: 4.785. PMID: 27933812

VOLNÁ, T., K. MOTYKA, J. HLAVÁČ. RP-HPLC determination of dissociation constant using solely aqueous mobile phase. Journal of Pharmaceutical and Biomedical Analysis. 2017, 134, 143-148. ISSN: 0731-7085. IF: 3.169. PMID: 27915191

CHROMÁ, K., M. MISTRÍK, P. MOUDRÝ, J. GURSKÝ, M. LIPTAY, R. STRAUSS, Z. ŠKROTT, R. VRTEL, J. BARTKOVA, J. KRAMARA, J. BÁRTEK. Tumors overexpressing RNF168 show altered DNA repair and responses to genotoxic treatments, genomic instability and resistance to proteotoxic stress. Oncogene. 2017, 36 (17), 2405-2422. ISSN: 0950-9232. IF: 7.932. PMID: 27841863

LITHWICK-YANAI, G., N. DROMI, A. SHTABSKY, S. MORGENSTERN, Y. STRENOV, M. FEINMESSER, V. KRAVTSOV, M. LEON, M. HAJDÚCH, S. ALI, C. VANDENBUSSCHE, C. ZHANG, L. LEIDER-TREJO, A. ZUBKOV, S. VOROBYOV, M. KUSHNIR, Y. GOREN, S. TABAK, E. KADOSH, H. BENJAMIN, T. SCHNITZER-PERLMAN, H. MARMOR, M. MOTIN, D. LEBANONY, S. KREDO-RUSSO, H. MITCHELL, M. NOLLER, A. SMITH, O. DATTNER, K. ASKHENAZI, M. SANDEN, K. BERLIN, D. BAR, E. MEIRI. Multicentre validation of a microRNA-based assay for diagnosing indeterminate thyroid nodules utilising fine needle aspirate smears. Journal of Clinical Pathology. 2017, 70 (6), 500-507. ISSN: 0021-9746. IF: 2.912. PMID: 27798083

JURÁŠEK, M., P. DŽUBÁK, S. RIMPELOVA, D. SEDLÁK, P. KONEČNÝ, I. FRYDRYCH, S. GURSKÁ, M. HAJDÚCH, K. BOGDANOVÁ, M. KOLÁŘ, T. MÜLLER, E. KMONICKOVA, T. RUML, J. HARMATHA, P. DRAŠAR. Trilobolide-steroid hybrids: Synthesis, cytotoxic and antimycobacterial activity. Steroids. 2017, 117, 97-104. ISSN: 1878-5867. IF: 2.513. PMID: 27543674

MATUŠKOVÁ, Z., P. ANZENBACHER, R. VECERA, M. ŠILLER, H. TLASKALOVA-HOGENOVA, J. STROJIL, E. ANZENBACHEROVÁ. Effect of Lactobacillus casei on the Pharmacokinetics of Amiodarone in Male Wistar Rats. European Journal of Drug Metabolism and Pharmacokinetics. 2017, 42 (1), 29-36. ISSN: 2107-0180. IF: 1.680. PMID: 26797809

AMBROŽOVÁ, N., B. ZALESAK, J. ULRICHOVÁ, K. ČÍŽKOVÁ, A. GALANDÁKOVÁ. Low concentration of silver nanoparticles have a beneficial effect on wound healing in vitro. Journal of Nanoparticle Research. 2017, 19, 108. ISSN: 1388-0764. IF: 2.101.

OKOROCHENKOVA, Y., J. HLAVÁČ. Novel ratiometric xanthene-based probes for protease detection. Dyes and Pigments. 2017, 143, 232-238. ISSN: 0143-7208. IF: 3.473.

KONC, J., M. TICHÝ, R. POHL, J. HODEK, P. DŽUBÁK, M. HAJDÚCH, M. HOCEK. Sugar modified pyrimidoij4,5-b]indole nucleosides: synthesis and antiviral activity. MedChemComm. 2017, 8, 1856-1862. ISSN: 2040-2503. IF: 2.608.