Škrott Zdeněk Ph.D.

Phone: +420 585632144

Groups: IMTM, LIG, POSTDOCTORAL FELLOW, STAFF

Junior researcher interested in protein homeostasis and degradation pathways in cancer and other diseases. Interested in microscopic techniques and live-cell imaging.

Author of 14 original scientific publications with over 600 SCI citations.

ŠKROTT, Z., D. MAJERA, J. GURSKÝ, T. BUCHTOVÁ, M. HAJDÚCH, M. MISTRÍK, J. BÁRTEK

Disulfiram's anti-cancer activity reflects targeting NPL4, not inhibition of aldehyde dehydrogenase. Oncogene. 2019, 38(40), 6711-6722, ISSN: 0950-9232, PMID: 31391554,

MAJERA, D., Z. ŠKROTT, J. BOUCHAL, J. BARTKOVA, D. ŠIMKOVÁ, M. GACHECHILADZE, J. STEIGEROVÁ, D. KURFÜRSTOVÁ, J. GURSKÝ, G. KOŘÍNKOVÁ, K. CWIERTKA, Z. HODNY, M. MISTRÍK, J. BÁRTEK

Targeting genotoxic and proteotoxic stress-response pathways in human prostate cancer by clinically available PARP inhibitors, vorinostat and disulfiram. The Prostate. 2018, 79(4), 352-362, ISSN: 0270-4137, PMID: 30499118,

ŠKROTT, Z., M. MISTRÍK, K. ANDERSEN, S. FRIIS, D. MAJERA, J. GURSKÝ, T. OŽDIAN, J. BARTKOVA, Z. TURI, P. MOUDRÝ, M. KRAUS, M. MEDVEDÍKOVÁ, J. VÁCLAVKOVÁ, P. DŽUBÁK, I. VROBEL, P. POUCKOVA, J. SEDLACEK, A. MIKLOVICOVA, A. KUTT, J. MATTOVA, C. DRIESSEN, Q. DOU, J. OLSEN, M. HAJDÚCH, B. CVEK, R. DESHAIES, J. BÁRTEK

Alcohol-abuse drug disulfiram targets cancer via p97 segregase adaptor NPL4. Nature. 2017, 552(7684), 194-199, ISSN: 0028-0836, PMID: 29211715,

1 Molecular and Translational Medicine

Project:	Cellular stress in health and disease
Supervisors:	Mistrík Martin Ph.D., Moudrý Pavel Ph.D., Škrott Zdeněk Ph.D.
Available:	3
Intended for:	Doctoral training

Škrott Zdeněk Ph.D.

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