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Academic title: M.Sc.
Phone: +420 585632068, +420 585632069
Groups: DOCTORAL STUDENT, IMTM, LEM, STAFF

Doctoral training

Development of a method for the sensitive and quantitative determination of hepcidin in human serum using LCMS

Hepcidin, a 25 amino acid peptide, plays an important role in iron homeostasis. As such, it has potential as an indicator of any iron-related condition, such as anemia. My research focuses on the measurement of hepcidin in biological fluids to improve our understanding of iron-related disorders. A possible result of such studies could be the development of hepcidin as a tool for diagnosis and clinical management of such disorders.

Specialization: Oncology
Status: Graduated from 2009 to 2016.

Journals

SKOPELIDOU, V., P. HURNIK, L. TULINSKY, V. ŽIDLÍK, J. LENZ, P. DELONGOVA, H. HORNYCHOVA, P. FLODR, T. JELINEK, L. MURONOVA, D. HOLUB, P. DŽUBÁK, M. HAJDÚCH
A unique case of AH-dominant type nodular pulmonary amyloidosis presenting as a spontaneous pneumothorax: a case report and review of the literature. Pathology & Oncology Research . 2023, 29, 1611390, ISSN: 1219-4956 , PMID: 37808084,  PDF.
CARNA, M., I. ONYANGO, S. KATINA, D. HOLUB, J. NOVOTNÝ, M. NEZVEDOVA, D. JHA, Z. NEDELSKA, V. LACOVICH, T. VYVERE, R. HOUBRECHTS, K. GARCIA-MANSFIELD, R. SHARMA, V. DAVID-DIRGO, M. VYHNALEK, K. TEXLOVA, H. CHAVES, N. BAKKAR, L. PERTIERRA, M. VINKLER, H. MARKOVA, J. LACZO, K. SHEARDOVA, M. HORTOVA-KOHOUTKOVA, J. FRIC, G. FORTE, P. KANOVSKY, S. BELASKOVA, J. DAMBORSKY, J. HORT, N. SEYFRIED, R. BOWSER, G. SEVLEVER, R. RISSMAN, R. SMITH, M. HAJDÚCH, P. PIRROTTE, Z. SPACIL, E. DAMMER, C. LIMBACK-STOKIN, G. STOKIN
Pathogenesis of Alzheimer's disease: Involvement of the choroid plexus. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 2023, ISSN: 1552-5260, PMID: 36825691,
OŽDIAN, T., J. VODICKA, J. DOSTÁL, D. HOLUB, J. VÁCLAVKOVÁ, M. JESETA, B. HAMERNÍKOVÁ, P. KOUŘILOVÁ, O. MALCHAR, V. DVORAK, P. HEJTMANEK, K. SOBKOVA, P. VENTRUBA, R. PILKA, P. DŽUBÁK, M. HAJDÚCH
Proteome Mapping of Cervical Mucus and Its Potential as a Source of Biomarkers in Female Tract Disorders. International Journal of Molecular Sciences. 2023, 24(2), 1038, ISSN: 1422-0067, PMID: 36674559,  PDF.

Books & book chapters

Proteomic analysis of complex samples by mass spectrometry, 1.vyd., Olomouc, Palacky University, 2021, 34, 265-268, Dedication: LO1304, ISBN: 978-80-244-6049-9,
Sample Preparation of Formalin-Fixed Paraffin-Embedded Tissue for Mass Spectrometry-Based Proteomic Analysis, 1.vyd., Olomouc, Palacky University, 2021, 35, 269-274, Dedication: LO1304, ISBN: 978-80-244-6049-9,

Master mentorship

Bartáková Anna

Typing of amyloid deposits by MS

Status: Ongoing from 2022.

Broskevičová Lucie

Typing of systemic amyloidosis using mass spectrometry-based proteomic analysis

Status: Graduated from 2014 to 2016.

Bachelor mentorship

Broskevičová Lucie

Využití hmotnostní spektrometrie pro identifikaci a kvantifikaci proteinových biomarkerů

Status: Graduated.

Holub Dušan Ph.D.

Subtyping of the amyloid deposits by mass spectrometry

Status: Ongoing from 2018 to 2020.

Open positions

1 Molecular and Translational Medicine
Project: New methods in protein degradation
Supervisors: Holub Dušan Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training