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Phone: +420 585632137
Groups: DOCTORAL STUDENT, IMTM, LEM, STAFF

Doctoral training

Detection and clinical importance of circulating tumor cells in solid tumours

The thesis is focused on the detection of circulating tumour cells (CTCs) by different approaches and the clinical importance of their presence in solid tumours, especially in lung, pancreatic and colorectal cancer patients. The main goal is to identify patients with high risk of disease recurrence and in need of adjuvant therapy. The second goal is to participate in the research and development of novel methods of CTCs detection and characterization.

Specialization: Pediatrics
Status: Ongoing from 2014.

About me

Researcher and postgradual student at the Institute of Molecular and Translational Medicine, Palacký University Olomouc, in the field of experimental and translational medicine. My research is focused on analysis of expression of opioid and cannabinoid receptors in tumor tissue.

Journals

SROVNAL, J., P. SKALICKÝ, A. PROKOPOVÁ, J. VRBKOVÁ, M. VIDLAŘOVÁ, M. DUDA, K. VYSLOUŽIL, M. HAJDÚCH
Long-term prognostic value of cytokeratin 20 mRNA-positive cells in blood and bone marrow of patients with localized colorectal cancer. Surgical Oncology. 2026, 65, 102367, ISSN: 0960-7404, PMID: 41719830,  PDF.
VECERA, L., P. PRASIL, J. SROVNAL, E. BERTA, M. VIDLAŘOVÁ, T. GABRHELIK, P. KOUŘILOVÁ, M. LOVEČEK, P. SKALICKÝ, J. ŠKARDA, Z. KALA, P. MICHALEK, M. HAJDÚCH
Morphine Analgesia, Cannabinoid Receptor 2, and Opioid Growth Factor Receptor Cancer Tissue Expression Improve Survival after Pancreatic Cancer Surgery. Cancers. 2023, 15(16), 4038, ISSN: 2072-6694, PMID: 37627066,  PDF.
ŘEHULKOVÁ, A., J. CHUDÁČEK, A. PROKOPOVÁ, M. VIDLAŘOVÁ, J. STRÁNSKÁ, J. DRÁBEK, J. POTOČKOVÁ, R. TROJANEC, J. VRBKOVÁ, J. ŠKARDA, T. BOHANES, M. SZKORUPA, B. TOLMACI, J. KLEIN, J. SROVNAL, M. HAJDÚCH
Clinical and prognostic significance of detecting CEA, EGFR, LunX, c-met and EpCAM mRNA-positive cells in the peripheral blood, tumor-draining blood and bone marrow of non-small cell lung cancer patients. Translational Lung Cancer Research. 2023, 12(5), 1034-1050, ISSN: 2226-4477 , PMID: 37323172,

Bachelor mentorship

Reichel Sebastian

Detection of circulating tumor cells

Status: Graduated from 2014 to 2018.