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Groups: BACHELOR STUDENT

Bachelor training

Cytogenetic changes in lung cancer patients

Bachelor’s thesis is focused on cytogenetic changes in lung cancer patients. Student will prepare a probe to investigate copy number of EGFR (located on chromosome 7) or the presence of inversion in ROS1 (located on chromosome 6) and ALK (located on chromosome 2). Status of these genes will be investigated by FISH method. Also another change will be detected – presence of HPV in lung cancer tissues using PCR.

Status: Graduated from 2016 to 2017.

Journals

TOMANOVÁ, M., K. KOZLANSKA, R. JORDA, L. JEDINÁK, T. HAVLIKOVA, E. ŘEZNÍČKOVÁ, M. PERINA, P. KLENER, A. DOLNÍKOVÁ, P. CANKAŘ, V. KRYŠTOF
Synthesis and Structural Optimization of 2,7,9-Trisubstituted purin-8-ones as FLT3-ITD Inhibitors. International Journal of Molecular Sciences. 2022, 23(24), 16169, ISSN: 1422-0067, PMID: 36555810,  PDF.