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Koudeláková Vladimíra Ph.D.

Journals

Evaluation of Non-Invasive Gargle Lavage Sampling for the Detection of SARS-CoV-2 Using rRT-PCR or Antigen Assay. Viruses. 2022, 14(12), 2829, ISSN: 1999-4915, PMID: 36560833,  PDF.
JAWOREK, H., V. KOUDELÁKOVÁ, I. OBORNA, B. ZBORILOVA, J. BREZINOVA, D. RUZICKOVA, J. VRBKOVÁ, P. KOUŘILOVÁ, M. HAJDÚCH
Impact of human papillomavirus infection on semen parameters and reproductive outcomes. Reproductive biology and endocrinology. 2021, 19(1), 156, ISSN: 1477-7827, PMID: 34627284,
KLEMPT, D., O. BRZON, M. KAŠNÝ, K. KVAPILOVA, P. HUBACEK, A. BRIKSI, M. BEZDICEK, V. KOUDELÁKOVÁ, M. LENGEROVA, M. HAJDÚCH, P. DREVINEK, S. POSPISILOVA, E. KRIEGOVA, E. KRIEGOVA, M. MACEK
Distribution of SARS-CoV-2 Lineages in the Czech Republic, Analysis of Data from the First Year of the Pandemic. Microorganisms. 2021, 9(8), 1671, ISSN: 2076-2607, PMID: 34442750,  PDF.

Books & book chapters

HER2 gene copy number detection by quantitative polymerase chain reaction (qPCR) , 1.vyd., Olomouc, Palacky University, 2021, 43, 343-350, Dedication: LO1304, ISBN: 978-80-244-6049-9,
Predictive Cancer Biomarkers: Current Practice and Future Challenges, 1.vyd, Boca Raton, CRC Press, 2019, 7.5, 383-394, ISBN: 978-1-4987-6258-8,
BOUCHALOVÁ, K., M. HAJDÚCH, J. BOUCHAL, A. HLOBILKOVA, M. HOUDOVÁ MEGOVÁ, M. HUDCOVÁ, V. KOUDELÁKOVÁ, J. MEDALOVA, J. SROVNAL, R. TROJANEC
Prediktivní a prognostická onkologie, 1. vyd, Olomouc, Univerzita Palackého v Olomouci, 2016, 122 s, Dedication: CZ.1.07/2.3.00/09.0089, ISBN: 978-80-244-3188-8,

Intellectual property

KIT FOR INVESTIGATING HER2 GENE STATUS IN SAMPLES OF BREAST CANCER SAMPLES USING QUANTITATIVE PCR METHOD (Koudeláková)
  1. Utility Model: CZ 28596, Granted: 7.9.2015, Ownership: Palacky University, Olomouc, Inventors: Koudeláková Vladimíra, Berkovcová Jitka, Trojanec Radek, Hajdúch Marián

Status: Excl. Licensed

RNA ISOLATION KIT (Džubák)

Utility Model: CZ 35067. Granted: 18.5.2021. Ownership: Palacky University, Olomouc. Inventors: Džubák Petr, Hajdúch Marián, Gurská Soňa, Koudeláková Vladimíra, Jaworek Hana.

Status: Available

Doctoral mentorship

Jaworek Hana Ph.D.

Human papillomavirus and its significance for diagnostics and therapeutics

Status: Graduated from 2012 to 2019.
Bouška Ondřej

Pathological conditions associated with human papillomavirus infection

Status: Ongoing from 2020.
Kubáňová Kateřina Mgr.

New prognostic and predictive factors in solid tumors

Status: Ongoing from 2023.

Master mentorship

Hanuláková Kristýna

HPV associated cancers

Status: Graduated from 2018 to 2020.
Jaworek Hana Ph.D.

Investigation of the pattern of expression of epigenetic modulators in normal and neoplastic tissue removed from female lower genital tract

Status: Graduated from 2012 to 2012.
Kubáňová Kateřina Mgr.

Methods for detection of high-risk Human Papillomavirus and its utility in primary cervical screening

Status: Graduated from 2019 to 2021.

Bachelor mentorship

Jaworek Hana Ph.D.

Polysomy of chromosome 17 in breast cancer patients and its impact for tailored therapy

Status: Graduated from 2010 to 2010.

Open positions

Project: Pathological conditions associated with human papillomavirus infection
Supervisors: Koudeláková Vladimíra Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary: High-risk human papillomavirus infection (HPV infection) is associated with several cancers such as cervical, vaginal, vulvar, head and neck, anal, and penile carcinomas. Nearly all cervical cancers are caused by HPV infection. Despite available vaccination and cervical cancer screening program, cervical cancer is one of the most common types of cancer affecting women worldwide. Main problems of cervical cancer screening are low participation rate and low sensitivity of cytology which is still used in the majority of cervical cancer screening programs. Solution could be the transition to primary HPV screening and the sending of self-sampling devices to cervical cancer screening non-attenders. The best strategy for enrolling Czech women in the screening program will be analysed during this project. Obtained samples will be tested for the presence of HPV DNA and the presence of other molecular biomarkers important in viral clearance and cervical cancer progression/regression. Discoveries will lead to identification of biomarkers for early diagnosis, disease progression or triage strategies. The aim of the project is to clarify the best strategy for enrolling women who do not attend cervical cancer screening program. The second aim is to study genetic and proteomic profile of HPV positive/negative women with normal/abnormal cervical cytology as well as genetic variants of HPV and its importance for regression/progression of the disease. Skills to be taught include biochemistry, molecular biology, bioinformatics and cell culture. This is an ideal project for a student who wishes to pursue higher studies in cancer research. The project will use various techniques including PCR, in situ hybridization, next generation sequencing, mass spectrometry.
Project: New prognostic and predictive factors in solid tumors
Supervisors: Hajdúch Marián M.D., Ph.D., Srovnal Josef M.D., Ph.D., Koudeláková Vladimíra Ph.D.
Available: 3
Intended for: Doctoral training
Project: Genetic and epigenetic biomarkers in health and disease
Supervisors: Slavkovský Rastislav Ph.D., Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D., Drábek Jiří Ph.D., Koudeláková Vladimíra Ph.D.
Available: 5
Intended for: Doctoral training
Project: Liquid biopsies in experimental and clinical oncology
Supervisors: Srovnal Josef M.D., Ph.D., Koudeláková Vladimíra Ph.D.
Available: 2
Intended for: Doctoral training