Štěpánková Jana

Groups: BACHELOR STUDENT

Preclinical development of 68Ga labelled peptides for glioblastoma imaging

This work is focused on preclinical testing of selected peptides labelled with 68Ga as potential radiodiagnostics for glioblastoma multiforme. The main goal of the study is to determine in vitro characteristics of studied peptides, their in vivo behaviour in mice and to evaluate the potential of 68Ga labelled peptides for diagnosis of glioblastoma multiforme using positron emisson tomography.

Supervisor: Petřík Miloš Ph.D.

Status: Graduated from 2014 to 2015.

GRUNER, B., J. BRYNDA, V. DAS, V. SICHA, J. ŠTĚPÁNKOVÁ, J. NEKVINDA, J. HOLUB, K. POSPISILOVA, M. FABRY, P. PACHL, V. KRAL, M. KUGLER, V. MAŠEK, M. MEDVEDÍKOVÁ, S. MATEJKOVA, A. NOVÁ, B. LIŠKOVÁ, S. GURSKÁ, P. DŽUBÁK, M. HAJDÚCH, P. ŘEZÁČOVÁ

Metallacarborane Sulfamides: Unconventional, Specific, and Highly Selective Inhibitors of Carbonic Anhydrase IX. Journal of Medicinal Chemistry. 2019, 62(21), 9560-9575, ISSN: 0022-2623, PMID: 31568723,

NOVÝ, Z., J. ŠTĚPÁNKOVÁ, M. HOLÁ, D. FLAŠAROVÁ, M. POPPER, M. PETŘÍK

Preclinical Evaluation of Radiolabeled Peptides for PET Imaging of Glioblastoma Multiforme. Molecules. 2019, 24(13), pii: E2496, ISSN: 1420-3049, PMID: 31288488,

CHOLYL HYDRAZONES AND THEIR USE IN THE TREATMENT OF TUMOR AND LEUKEMIA DISEASES (Rak)

Patent: CZ 305607; Granted: 25.11.2015; Ownership: Institute of Chemical Technology Prague, Palacky University Olomouc, Institute of Molecular Genetics CAS; Inventors: Rak Jakub, Kaplánek Robert, Štulcová Tereza, Drašar Pavel, Havlík Martin, Bříza Tomáš, Džubák Petr, Hajdúch Marián, Konečný Petr, Š těpánková Jana, Králová Jarmila, Král Vladimír

Status: Terminated

Štěpánková Jana

Bachelor training

Journals

Intellectual property