Czech Republic

IODINATED ANALOGS OF CHOLINE, METHODS OF PREPARATION THEREOF, AND USE THEREOF AS MEDICAMENTS. Inventors: Švec, P., M. Hrubý, J. Kučka, O. Sedláček, M. Petřík, Z. Nový, M. Hajdúch.
Priority application: CZ PV 2016-117
Published: WO 2017/148455 (08.09.2017), EP 3423441 (09.01.2019)
Ownership: Ustav makromolekularni chemie AV CR, Univerzita Palackeho v Olomouci.

METHOD OF PREPARATION OF A SOLUBLE FORMULATION OF WATER-INSOLUBLE PENTACYCLIC AND TETRACYCLIC TERPENOIDS, A SOLUBLE FORMULATION OF A PENTACYCLIC OR TETRACYCLIC TERPENOID AND A PHARMACEUTICAL COMPOSITION CONTAINING THIS SOLUBLE FORMULATION. Inventors: Šarek, J., M. Hajdúch, M. Svoboda, K. Nováková, P. Spáčilová, T. Kubelka, D. Biedermann.
Priority application: CZ PV 2006-606
Published: WO 2008/037226 (03.04.2008), EP 2068882 (23.08.2017)
Ownership: Univerzita Karlova v Praze, Univerzita Palackeho v Olomouci, I.Q.A.

SUBSTITUTED 7-DEZAPURIN RIBONUCLEOSIDES. Inventors: Hocek, M., P. Nauš , O. Caletková, P. Džubák, M. Hajdúch.
Priority application: CZ PV 2013-845
Published: US 9,586,986 (07.03.2017), CZ 305466 (07.09.2015)
Ownership: Ustav organické chemie a biochemie AV CR, Univerzita Palackeho v Olomouci, 

METHOD OF DETERMINATION OF CANCER CELL DRUG SENSITIVITY TOWARDS AURORA KINASE INHIBITORS AND OVERCOMIMG THEIR RESISTANCE. Inventors: Kollaredy, M., M. Hajdúch, P. Džubák, J. Srovnalf, Hrabáková, Kovářová Hana.
Priority application: EP 11192330.6
Published: JP 6144696 (19.05.2017)
Ownership: Univerzita Palackeho v Olomouci, Ustav zivocisne fyziologie a genetiky AV CR

A METHOD OF STABILIZING ANTIBODIES RECOGNIZING 5-BROMO-2'-DEOXYURIDINE AND/OR 5-CHLORO-2'-DEOXYURIDINE AND/OR 5-IODO-2'-DEOXYURIDINE AT SITES OF INCORPORATION OF THESE NUCLEOSIDES INTO THE DNA AFTER TREATMENT WITH MONOVALENT COPPER AND/OR EXONUCLEASE III. Inventors: Koberna Karel, Ligasová Anna.
Priority application: CZ PV 2015-183
Published: CZ 307 016 (04.10.2017)
Ownership: Univerzita Palackeho v Olomouci

METHOD OF PREDICTING THE TUMOR RESPONSE TO DNA METHYLATION INHIBITORS AND ALTERNATIVE THERAPEUTIC REGIMENS FOR OVERCOMING RESISTANCE. Inventors: Agrawal K., I. Frydrych, P. Džubák, M. Hajdúch.
Priority application: EP 14161897.5
Published: EP 2924125 (17.06.2017) 
Ownership: Univerzita Palackeho v Olomouci

BENZOISOTHIAZOLE-1, 1-DIOXIDE-3-HYDRAZONES AND THEIR USE IN ANTICANCER THERAPY. Inventors: Kaplánek R., T. Bříza, M. Havlík, J. Rak, Z. Kejík, P. Džubák, M. Hajdúch, P. Konečný, J. Štěpánková, J. Králová, V. Král.
Priority application: PV 2014-322
Published: CZ 306554 (25.01. 2017)
Ownership: Vysoka skola chemicko-technologicka v Praze, Univerzita Palackeho v Olomouci, Ustav molekularni genetiky AV CR

DEVICE FOR STORAGE, TRANSPORT AND APPLICATION OF STEM CELLS. Inventors: Petrenko, Y., E. Syková, J. Čejková, I. Vacková, T. Groh.
Priority application: CZ PV 2016-284
Published: CZ 306800 (12.07.2017)
Ownership: Ustav experimentalni mediciny AV CR

PHOTOACTIVATABLE NANOPARTICLES FOR PHOTODYNAMIC APPLICATIONS, METHOD OF PREPARATION THEREOF, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND USE THEREOF. Hruby, M., I. Brezaniova, V. Kral. 
Priority application: CZ PV 2016-119
Published: WO 2017/148454 (08.09.2017), CZ 307681 (03.01.2019)
Ownership: Ustav makromolekularni chemie AV CR, Vysoka skola chemicko-technologicka v Praze